acquired via close contact with young children, as seen in this patient, and maternal infection can result in either a subclinical or mild febrile illness. During this maternal infection, transplacental (vertical) transmission can occur and cause fetal infection. CMV spreads throughout the fetus and preferentially replicates in the placenta, liver, and central nervous system, resulting in the clinical features
| Ultrasound findings | • bilateral Periventricular calcifications (ie, due to tissue necrosis) • Ventriculomegaly • Microcephaly • Intrahepatic calcifications • Fetal growth restriction • Hydrops fetalis | | --- | --- | | Neonatal features | • Petechiae • Hepatosplenomegaly • Chorioretinitis • Microcephaly | | Long-term sequelae | • Sensorineural hearing loss • Seizures • Developmental delay |
<aside> 💡 Maternal infection is diagnosed via serology, and fetal infection is diagnosed via amniocentesis. Maternal antiviral therapy is not indicated as it has not been proven to prevent fetal infection.
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