Patients with recent unprotected sexual intercourse or contraception failure (eg, broken condom) are at risk for unintended pregnancy and may be candidates for emergency contraception

Pregnancy status determines eligibility for EC use:

<aside> 💡 Most states allow adolescents to receive confidential care for contraception, pregnancy, and sexually transmitted diseases without parental consent

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Method Timing after intercourse Efficacy Contraindications
Copper-containing intrauterine device 0-120 hr >99% • Wilson disease
• Active pelvic infection
• Severe uterine cavity distortion
Progestin-releasing intrauterine device 0-120 hr >99% • Breast cancer
• Active pelvic infection
• Severe uterine cavity distortion
Ulipristal 0-120 hr 98%-99% • None
Oral levonorgestrel (ie, Plan B) 0-72 hr 92%-98% • None
Oral contraceptives ( Combined estrogen/progestin oral contraceptive pills containing levonorgestrel or norgestrel) 0-72 hr 75%-89% • None

In addition to being the most effective method of emergency method of contraception an IUD can be left in place to provide continued contraception.

Levonorgestrel and ulipristal pills are EC methods that prevent pregnancy primarily by delaying ovulation ( same moa of COCs use in emergency contraception) . Although these medications are more accessible than an IUD, which requires a provider trained in its insertion, they are slightly less effective at pregnancy prevention than an IUD and do not offer the benefit of continued contraception.

The levonorgestrel pill (ie, Plan B) is the most readily available form of EC; the high dose of progestin in these pills prevents pregnancy by inhibiting the LH surge, thereby delaying ovulation. Additional mechanisms include cervical mucus thickening and thinning of the endometrial lining.  Levonorgestrel pills are highly effective (ie, up to 94%); however, effectiveness decreases over the course of 72 hours (ie, as low as 59%).  Therefore, levonorgestrel pills should be provided as soon as possible after unprotected intercourse.

ulipristal pill, a progestin receptor blocker that prevents pregnancy by delaying ovulation and impairing implantation.  Ulipristal can be taken up to 120 hours after unprotected intercourse; however, it should be administered as soon as possible because its effectiveness decreases with time.

Choice A)  Combination oral contraceptives, commonly used for precoital contraception, may also be used for EC by taking multiple pills simultaneously to achieve the progestin level required to delay ovulation.  However, the high estrogen content typically causes intolerable side effects (eg, severe nausea), and this method is less effective (ie, 47%-89%) than ulipristal & levonorgestrel pills..

(Choices C and E)  A progestin-releasing subdermal implant is a long-acting, reversible contraceptive used for precoital contraception.  Because it provides sustained release of low-dose progestin, it cannot achieve the acute increase in progestin levels required to delay ovulation for EC.  Similarly, the transdermal estrogen-progestin patch is a slow-releasing combined hormonal contraceptive used only for precoital contraception.