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Physiologic leukorrhea

Vaginitis

Labial adhesions

Vulvar lichen sclerosus

Vulvar lichen planus

Vulvar vitiligo

Candida Intertrigo

Genitourinary syndrome of menopause (atrophic vaginitis)

Rectovaginal fistula

Vesicovaginal fistula

Bartholin gland cyst/fistula

Genital warts (condylomata acuminata)

Hidradenitis suppurativa

Vaginal foreign bodies

Vulvar cancer

Vaginal cancer

Women exposed to diethylstilbestrol (DES) in utero are at increased risk of clear cell carcinoma of the cervix and vagina.

Seminal plasma allergy typically presents with systemic anaphylaxis, although primarily local symptoms may also occur. With local reactions, symptoms include vulvovaginal pruritus and edema. In addition, symptoms are typically associated with recent sexual activity, and condom use is protective.

Topical corticosteroids are the treatment for desquamative inflammatory vaginitis, which often presents with copious watery discharge.  In contrast to this patient, those with desquamative inflammatory vaginitis have an inflamed erythematous vagina on pelvic examination and a predominance of leukocytes on wet mount microscopy.

pinworms can cause vulvovaginitis in some cases

Desquamative inflammatory vaginitis can cause vulvar pain and abnormal vaginal discharge.  However, vulvar architecture is maintained (eg, no erosive vulvar lesions), and concomitant oral lesions would not be expected.

Sarcoma botryoides, a type of embryonal rhabdomyosarcoma, can present as a genitourinary mass, but it is typically vaginal and exclusively diagnosed in infants, not postmenopausal patients.

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